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You may have very low blood pressure while taking this medication. Chloromycetin Eye Drops or Ointment and some other medicines may interfere with each other. Retrieved from http://abcnews. In double-blind clinical trials involving GLUCOVANCE as initial therapy or as second-line therapy, a total of 642 patients received GLUCOVANCE, 312 received metformin therapy, 324 received glyburide therapy, and 161 received placebo. Only certain progestins are androgenic however, these being the testosterone derivatives and, to a lesser extent, the 17О±-hydroxyprogesterone derivatives medroxyprogesterone acetate and megestrol acetate. Tan, Paul (4 August 2008).